Mannatech Announces New Antioxidant Product; Unique Synergistic Blend Key Component of New Product

COPPELL, Texas, Sept. 12 -- Mannatech, Inc. (Nasdaq: MTEX) announced today the newest addition to its Optimal Health products, Ambrotose AO(TM).

The new Mannatech anti-oxidant product, which is both proprietary and patent pending, has been designed to help counter the harmful effects of toxins, other environmental sources of stress, daily physical stress and poor diet-all of which can damage your body's DNA, cells and tissues and lead to premature aging.*

"All antioxidant products are not created equal," said Mannatech Chairman and CEO Sam Caster. "The 'synergy' -- the capability of component parts to act together for best possible results -- is a key piece of what sets Ambrotose AO(TM) apart from all the rest." Caster added, "In Ambrotose AO(TM), we have combined the benefits of our newly discovered antioxidant blend with our patent pending flagship technology, Ambrotose complex."

Laboratory studies and tests conducted by Mannatech have demonstrated that Mannatech's MTech AO Blend(TM) used in Ambrotose AO(TM) far outdistanced 90 different antioxidant products and tested three times more powerful than the next leading competitive product tested. MTech AO Blend(TM) was tested with both the existing ORAC method and the new patent-pending ORACo method developed by Mannatech.** Ambrotose AO(TM) gains its unique advantage from a synergistic AO Blend (patent pending) designed to support health and assist in the fight of harmful free radicals caused by oxidative stress.* Oxidative stress is caused by toxins (poisons) in our environment, which are now found in virtually everything with which we come in contact, including our atmosphere, water, soil, food and most synthetic products. Toxic chemical assault produces "free radicals" -- the by-products of oxidative stress that damage human cells.

Ambrotose AO(TM) contains no animal products, no fillers and none of the excipients typically used in manufacturing these types of products. One hundred percent of the ingredients in Ambrotose AO(TM) are functional.

"Most antioxidants on the market today are single ingredients combined together for an additive effect," said Dr. Stephen Boyd MD, PhD, FRSM, Mannatech's Medical Director and Administrator of the Medical Research department. "Mannatech has taken a new approach and we have filed for patent protection for a new test method which measures true antioxidant potential of a product. In doing this, we believe we have discovered a unique combination of ingredients that is not only additive but is also synergistic in its effect." In a paper published in the American Journal of Clinical Nutrition in 1998, researchers at the US Department of Agriculture concluded that increasing the intake of fruits and vegetables in a healthy study population from their usual five to an experimental ten servings a day significantly increased the plasma antioxidant capacity by approximately 13%. By comparison, initial clinical studies with Ambrotose AO(TM) over the same time period resulted in an increase in the plasma antioxidant capacity of at least twice that percentage. Ambrotose AO(TM) is designed to help supplement your daily antioxidant intake in addition to your daily servings of fruits and vegetables.

The new Mannatech Ambrotose AO(TM) product is designed to assist in the following:

-- Protect against toxins, poor food, stress and the environment, all
of which cause the influx of free radicals that can accelerate the
aging process*
-- Defend your health by supporting overall immune function through
natural glyconutrients*
-- Help restore damage done to your body from the harmful effects of free
-- Speed up and support your body's natural cellular capability for
cellular repair*

"Mannatech is committed to optimal health and providing our valued customers with a complete and comprehensive wellness solution," said Caster. "We believe the Mannatech Ambrotose AO(TM) product should be the cornerstone of your personal wellness plan."

About Mannatech

Based in Coppell, Texas, Mannatech, Inc. is a wellness solutions provider that develops innovative, high quality, proprietary nutritional supplements, topical products and weight management products which are sold through a global network marketing system throughout the United States and the international markets of Canada, Australia, the United Kingdom, Japan and New Zealand.

This release may contain "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995. Such statements are subject to certain events, risks and uncertainties that may be outside of Mannatech's control. Actual results and developments could materially differ from those expressed in or implied by such statements due to a number of factors. In some cases, forward-looking statements may be identified by terminology such as "may," "should," or "believes," or "designed," or the negative of such terms and other comparable terminology. Although Mannatech believes that the expectations reflected in these forward-looking statements are reasonable, it cautions its readers to consider the risk factors and any other cautionary statements in this release, as well as those set forth in Mannatech's filings with the Securities and Exchange Commission. All of the forward-looking statements contained herein speak only as of the date of this press release.

**ORAC, an acronym for Oxygen Radical Absorption Capacity, is a chemical analysis that measures the total antioxidant potency of foods and other chemical substances.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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